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Found 344 Barrett's Esophagus trials

A listing of Barrett's Esophagus medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 ADP-0000-002: Long Term Follow-up of Subjects Exposed to NY-ESO-1c259 T  A Genetically Engineered NY-ESO-1 Specific T Cell Receptor
99 years or below
All genders
This non-therapeutic, multi-center LTFU study involves up to 15 years post-infusion monitoring of subjects who have been exposed to lentivirus-mediated gene transfer in Adaptimmune clinical studies. Subjects will undergo clinical evaluation with careful attention to adverse events possibly related to gene transfer/lentivirus-induced diseases. Blood samples will be collected. Subjects will …
99 years or below
All genders
Medication is FDA approved. The present study is a further evaluation of the behavioral pharmacotherapeutic strategy (i.e., partial reinforcement following the obtention of treatment response with standard treatment) with a particular focus on 1) how low a dose may be used (dose = frequency of active medication) and 2) how …
99 years or below
All genders
Phase 2
This is a single-center, phase II, single-arm, open label study evaluating the efficacy and safety of abemaciclib for patients with recurrent oligodendroglioma (molecularly defined per the WHO 2016 guidance, i.e., presence of IDH mutation and 1p19q codeletion). The study will enroll 10 subjects who are evaluable for the studys primary …
99 years or below
All genders
Phase 1
Adults 65 and older are more likely to have significant injuries from minor things like falls. They can have problems regaining strength due to sarcopenia (loss of muscle tissue as part of natural aging process). Nicotinamide riboside/pterstilbene (Basis) is commercially available nutraceutical. This randomized, double blind placebo controlled trial will …
 Multimodal imaging outcome measures for ALS (Image ALS)
18 years - 90 years
All genders
Phase 1
This research study is being done to learn more about changes over time in Positron Emission Tomography/Computed Tomography (PET/CT) imaging in people with amyotrophic lateral sclerosis (ALS).  We need data from people with ALS. If you agree to be in this study, you will have up to 6 PET/CT scans …
 Determination of B-cell responsiveness to the incretin hormones GLP-1 and GIP in Cystic Fibrosis (PRIME)
18 years - 99 years
All genders
The mechanisms underlying cystic fibrosis related diabetes (CFRD) pathophysiology must be better defined if care for people with CFRD is to be optimized or if development of CFRD is to be interrupted. Detailed studies of insulin secretion in CF are required to achieve this goal since 1) subtle insulin secretion …
 Transcatheter Aortic Valve Replacement to UNload the Left ventricle in patients with ADvanced heart failure
99 years or below
All genders
Randomized (flip of the coin 50/50) study of heart failure (HF) patients with moderate aortic valve stenosis (narrowing) will be either treated with a transcatheter valve replacement (TAVR) or continue with medical management. Subjects will be followed for 2 years. We will collect information regarding death and major events such …
99 years or below
All genders
Use of an HIV+ deceased donor could increase the risk of death, transplant-related or HIV-related complications; alternatively with effective antiretroviral treatment and careful HIV+ donor selection, these risks may be comparable to kidney transplant using an HIV-negative donor. We hypothesize that receiving a kidney transplant from an HIV+ donor will …
 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Sarilumab in Giant Cell Arteritis
18 years - 87 years
All genders
Phase 3
The main purpose of this study is to understand how well giant cell arteritis (also known as temporal arteritis; GCA) responds to an investigational drug called sarilumab. Sarilumab needs to be tested to find out if it is safe and effective in treating GCA. An investigational drug is one that …
 Cardiovascular Inflammation Reduction Trial (CIRT):  A randomized  double-blind  placebo controlled  event-driven trial of weekly low-dose methotrexate (LDM) in the prevention of recurrent cardiovascular events among stable post-myocardial infarction patients with type 2 diabetes or metabolic syndrome
1 years - 99 years
All genders
Phase 4
This is an event-driven, multi-center, randomized, double-blind, placebo-controlled trial to determine whether methotrexate reduces heart attacks, strokes, or death in people who have already had at least one heart attack and have type 2 diabetes or metabolic syndrome. Metabolic syndrome is defined as a combination of problems including a large …
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