Found 706 All Conditions trials
A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Subjects with Stage III resectable melanoma will receive adjuvant therapy, nivolumab or ipilimumab plus nivolumab, based on whether a pathologic complete response (CR) or near CR (less than 10% viable tumor cells) is achieved with one dose of nivolumab in the neoadjuvant setting followed by surgery.
The purpose of this study is to evaluate the performance of the EchoMark and EchoSure (both FDA approved devices) as an ultrasound-based method of monitoring the viability of free flaps and patency of at-risk vessels. The implant and ultrasound will be used per IFU. The primary purpose of the study …
The main purpose of this study is to understand how well giant cell arteritis (also known as temporal arteritis; GCA) responds to an investigational drug called sarilumab. Sarilumab needs to be tested to find out if it is safe and effective in treating GCA. An investigational drug is one that …
This trial is a phase 3, double-blind, placebo-controlled, randomized withdrawal maintenance trial of brexpiprazole in subjects who require adjunctive treatment of MDD designed to fulfill a post-marketing commitment to the US Food and Drug Administration (FDA). There is a paucity of data on long-term use of the combination of ADT …
Adult HIV prevalence in Botswana is estimated at 25%. In 2013, despite widespread availability of antiretroviral therapy (ART), an estimated one-quarter of patients did not initiate ART until their CD4 count was below 147 cells/microL. The early mortality rate in these individuals is high, and cryptococcal meningitis is a leading …
Two arm, randomized controlled trial with sham therapy control arm to assess the efficacy of low-frequency trans-cutaneous magnetic stimulation of the autonomic nerves in the neck for patients with ventricular arrhythmia. Twenty two (22) subjects with a high burden of ventricular arrhythmia will be randomized to undergo 60-minutes of low …
Patients with bloating associated with irritable bowel syndrome (IBS) will be invited to participate in the study. Study to investigate the role of bacteria in the gastrointestinal tract (gut microbiome) in various patients with IBS. The purpose of this study is to characterize the gut bacteria and their associated molecules …
The longstanding view has been that insomnia, and other forms of sleep disturbance, emerge as a consequence of dementia and are the result of progressive neuronal damage. However, there is growing evidence that the direction of causation may go both ways, with sleep disturbance potentially increasing vulnerability to dementia. Longitudinal …
The purpose of this program is to allow patients who, in consultation with their treating physician, feel it is in their best interest to continue to receive olaratumab. Only patients with soft tissue sarcoma who are already being treated with olaratumab may enter this program.
