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Found 700 All Conditions trials

A listing of All Conditions medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

A Study to Evaluate the Safety and Efficacy of Image Guided Surgery using Indocyanine Green for Intramolecular Imaging of Solid Tumors Compared to Standard of Care (TumorGlow) (PRIME)

99 years or below
All genders
Phase 2
Indocyanine Green (ICG) is an FDA approved, water-soluble tricarbocyanine dye routinely used in clinical settings for measuring cardiac output, liver function, and retinal angiography and has been in use for over 50 years. Patient diagnosed with solid tumor cancers have a high rate of recurrence when surgery is a treatment. …
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Early diagnosis of transthyretin cardiac amyloidosis

99 years or below
All genders
Disease modifying therapies for ATTR transthyretin cardiac amyloidosis (ATTR-CA) promises to make a previously untreatable disease manageable. In general, cardiac amyloidosis of any type has been shown to be underdiagnosed or diagnosed late in the disease process. Our goal of the study is to identify African American (AA) patients who …
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THE AURORA STUDY- Longitudinal Assessment of Post-traumatic Syndromes

99 years or below
All genders
See Protocol Section 1
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A Trial of Crizanlizumab for the Treatment of Retinal Vasculopathy with Cerebral Leukoencephalopathy (RVCL)

99 years or below
All genders
Phase 2
Retinal vasculopathy with cerebral leukoencephalopathy (RVCL) is a very rare and fatal genetic condition that affects the smallest blood vessels, especially of the brain and eye. It causes damage in the brain and eye, and there is currently no treatment to reduce these areas of damage. Crizanlizumab has been shown …
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UPCC 23220 Vitamin D Receptor Agonist Paricalcitol Plus Gemcitabine and Nab-Paclitaxel in Patients with Metastatic Pancreatic Cancer

99 years or below
All genders
Phase 1
This research study consists of a safety run-in phase and a randomized phase 2 study which include subjects with previously-untreated, metastatic pancreatic adenocarcinoma. In the run-in safety study, the safety of adding two formulations (IV or Oral) of paricalcitol to a standard chemotherapy program of gemcitabine and nab-paclitaxel will be …
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TOOLs MRI Evaluation of the Human Placenta

99 years or below
All genders
See protocol section 2, Abstract
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Effect of GLP-1 Agonist Therapy on Insulin Secretion in Adults with Pancreatic Insufficient Cystic Fibrosis and Abnormal Glucose Tolerance: a randomized open-label cross-over trial

99 years or below
All genders
Diabetes is a major co-morbidity in pancreatic insufficient cystic fibrosis (PI-CF) and associated with worse outcomes. While reduced -cell mass contributes to the insulin secretory defects that characterizes cystic fibrosis-related diabetes (CFRD), other modifiable determinants appear operative in the emergence and progression of abnormal glucose tolerance towards diabetes. Identifying interventions …
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A Randomized study of EHR Defaults and Using social Comparison feedback to Effectively decrease opioid prescription pill burden - The REDUCE Trial

99 years or below
All genders
Opioid-related abuse and overdose represent a growing national epidemic in the United States. Clinician practice patterns play an important role: opioid prescriptions impact the likelihood that patients will misuse or become dependent on these medications, with longer prescriptions leading to greater sustained use. In this study, we will evaluate a …
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A prospective randomized active (warfarin) controlled parallel-arm clinical trial to determine if patients with an On-X aortic valve can be maintained safely and effectively on the factor Xa inhibitor apixaban (PROACT-Xa Trial)

99 years or below
All genders
Phase 1
The purpose of this study is to determine if participants with an On-X Prosthetic Heart Valve / On-X aortic valve (a type of mechanical valve) can be maintained safely and effectively on apixaban, an anticoagulant drug different from warfarin.
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UPCC 20818: A Phase 2 Study to Evaluate Safety and Anti tumor Activity of Avelumab in Combination with Talazoparib in Patients with BRCA or ATM Mutant Tumors

99 years or below
All genders
TBD
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