A listing of healthy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The UNTIL Trial is a new clinical research trial that offers uterine transplantation to women with uterine factor infertility (UFI). Participation in this trial requires going through an extensive selection process, creation of embryos through in vitro fertilization, and multiple surgeries. Study participants may remain in the study for 5-10 …
The Universal COVID-19 Biobank – a component of the Penn Medicine Biobank – is collecting and storing biological specimens as well as information about people who may or may not have been exposed to the SARS-CoV-2 virus as well as those who have developed COVID-19 disease. This information will be …
To support the research of kidney disorders by creating a bank of biospecimens and a corresponding database of clinical information that will be used for future, unspecified research. Target population is adults with a kidney disorder, but the study also allows for enrollment of family members, healthy controls, and children. …
Glucose is a major energy source for brain cells. Changes in blood glucose also leads to changes in supply or availability of glucose to brain cells. Changes in various brain metabolites when mapped in different areas of the brain will allow, an understanding of the effects of such changes in …
Obesity is strongly regulated by energy expenditure, but the variables regulating individual levels of energy expenditure in the human population remain unknown. This study examines the parameters regulating energy expenditure at rest and during exercise in healthy adults across the lifespan. Participants will fill out a questionnaire and provide blood, …
Traumatic cerebrovascular injury (TCVI) is common after traumatic brain injury (TBI) and an attractive target for therapeutic intervention. We will longitudinally measure cerebrovascular reactivity (CVR) by functional near-infrared spectroscopy (fNIRS) in acute (3 days from injury), subacute, and chronic phases after TBI as a biomarker of TCVI as compared to …
Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in the treatment of pain and inflammation. Mounting evidence indicates that rectal administration of NSAIDs is also effective in preventing pancreatitis following endoscopic retrograde cholangiopancreatography (ERCP) by an unknown mechanism. Alterations in the salivary and fecal microbiome have been observed in patients with …
The specific Aims of CAPS5 will be: Aim #1: To evaluate pancreatic fluid mutations and circulating pancreatic epithelial cells as accurate markers of neoplasia by comparing their prevalence in cases with sporadic pancreatic neoplasia to healthy and disease controls. Aim #2: To compare the prevalence of pancreatic fluid mutations and …
The purpose of this study is to determine whether tracing data (maternal and fetal heart rate) collected remotely on the Nuvo Invu device can be used for clinical management of pregnant patients. We will be recruiting generally healthy pregnant women with singleton gestations who at at least 32 weeks gestation …
Attention Deficit Hyperactivity Disorder (ADHD) is characterized by symptoms of impulsivity, inattention, and hyperactivity that emerge in childhood and frequently persist into adulthood. These symptoms are accompanied by deficits in cognitive control and risky decision making that can lead to negative psychosocial and health-related outcomes. With advances in the neuroimaging …