A Phase 1/2 Study of Oral LOXO-292 in Patients

Recruiting
99 years or below
All
Phase 1
5 participants needed
1 Location

Brief description of study

LOXO-292 is a highly potent and specific inhibitor of the RET RTK, with minimal inhibition of other kinase and non-kinase targets, and therefore may be of benefit to patients with tumors (such as NSCLC, MTC, PTC, and colon or breast carcinomas) that harbor RET alterations and/or depend on RET activation. This Phase 1/2 study of LOXO-292 is required to understand the PK, safety, and maximum tolerated dose (MTD) for LOXO-292 in patients and to permit the preliminary assessment of efficacy.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

  • Conditions: TBD
  • Age: 99 years or below
  • Gender: All
Updated on 19 Feb 2024. Study ID: 830166

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