Clinical Characterization of Inherited Patterned Lentiginosis

Inherited lentigines syndromes are characterized by multiple small, light to very dark brown or black evenly pigmented macules. Several of these syndromes are associated with systemic abnormalities including predisposition to internal malignancy. Inherited Patterned Lentiginosis is an autosomal dominant syndrome for which the genetic mutation(s) have yet to be elucidated. This observational case-series will carefully describe the clinical phenotype of Inherited Patterned Lentiginosis. Additionally, this study will investigate the genetic mutation(s) associated with IPL through genotyping of DNA obtained from saliva samples from affected and non-affected family members.

You may be eligible for this study if you meet the following criteria:

• Conditions: TBD, tbd, tbd
• Age: 99 years or below
• Gender: All