MOXI: Males, Antioxidants, and Infertility | Clinical Research Studies Listing

Recruiting

18 years - 100 years

Male

50 participants needed

1 Location

Brief description of study

MOXI is a research study to examine whether antioxidants can improve abnormal semen parameters in couples with male-factor infertility. Eligible male participants will be randomized to either an antioxidant supplement or placebo for 3 months, followed by fertility treatment with ovarian stimulation and intrauterine insemination.

Detailed description of study

MOXI Phase I will involve randomization to either an antioxidant supplement or placebo. This study is blinded, such that neither the participant nor the study team will know which treatment is assigned. After 3 months of treatment (with the assigned study drug), couples will be receive up to 3 consecutive cycles of female ovarian stimulation with an oral medication (clomiphene citrate), triggered ovulation with hCG, and a single intrauterine insemination (Phase II). Couples who conceive in either Phase I or Phase II will be followed through pregnancy and delivery. Male subjects will take their assigned study drug for at least 3 and up to 6 months.

Eligibility of study

You may be eligible for this study if you meet the following criteria:

Conditions: Male Infertility
Age: 18 years - 100 years
Gender: Male

Updated on 19 Feb 2024. Study ID: 821457

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