Search filters

Filters
Clear All

Phase

  • 1
  • 3
  • 5
  • 1
  • 5

Found 5 Tobacco Use Disorder trials

A listing of Tobacco Use Disorder medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

14 years - 18 years
All genders
The University of Pennsylvania is conducting a study of brain responses to graphic health warnings. The study includes receiving cell phone messages for 4 weeks and two functional Magnetic Resonance Imaging (fMRI) scans of the brain. These scans are non-invasive and do not use X-ray. To be eligible to participate, …
 The influence of nicotinic hepatic metabolism on neuroreceptor substrates of nicotine addiction
18 years - 99 years
All genders
Phase 1
We will examine differences in nAChR availability based on individual differences in the nicotine metabolism rate. Work conducted by Dr. Lermans group at Penn, in collaboration with Drs. Rachel Tyndale (University of Toronto) and Neal Benowitz (University of California, San Francisco) has documented differences in smoking cessation and treatment response …
 Daily Liraglutide for Nicotine Dependence
18 years - 99 years
All genders
We are currently recruiting smokers who are interested in quitting for a research study that involves taking a medication called liraglutide. Liraglutide is also marketed under the name Saxenda®.Liraglutide is an injectable medicine that may help some adults with who are overweight or obese lose weight and keep the weight …
 Targeting the Cholinergic Pathway in HIV-associated Inflammation and Cognitive Dysfunction
40 years - 100 years
All genders
Although anti-retroviral therapy (ART) enhances life expectancy and overall quality of life (QoL), HIV-infected individuals are increasingly vulnerable to non-AIDS-related diseases including HIV-associated neurocognitive disorders (HAND). Inflammation is a primary mechanism in the pathogenesis of HAND and tobacco use may further exacerbate inflammation. Conversely, nicotine alone has anti-inflammatory effects suggesting …
 Measurement of Pulmonary Inflammation Using F-NOS Positron Emission Tomography (PET/CT) in E-cigarette Users
18 years - 45 years
All genders
This is a 1 – 2 month study examining the extent of lung inflammation between e-cigarette smokers, cigarette smokers, and non-smokers using a new radio tracer, FNOS. FNOS is an experimental radio tracer used to look for inflammation in different parts of the body. The tracer that we will be …