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Found 47 Surgery trials

A listing of Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Surgical Therapy for Obstructive Sleep Apnea on Blood Pressure & Peripheral Arterial Tonometry
18 years - 90 years
All genders
The research study is being done to look at the effect of sleep apnea surgery on different measures ofcardiovascular (heart) function in people with obstructive sleep apnea.
18 years - 90 years
Female
The goal of this clinical research study is to compare the changes in female sexual function between patients having interval salpingectomy with delayed oophorectomy (ISDO) with those having risk-reducing salpingo-oophorectomy (RRSO) in women who carry genetic mutations. Researchers also want to learn how these surgeries affect your quality of life. …
 To Serenade or To Sedate? That is Still The Question - A Followup Trial On Anxiolytic Options Before Peripheral Nerve Blocks
99 years or below
All genders
The research study is being conducted to determine if there are differences in anxiety scores, heart rate, blood pressure, and oxygen status when using sedation medication versus the patient's choice of listening to music while undergoing a peripheral nerve block before his or her surgery. The patient will either receive …
99 years or below
All genders
Phase 2
Subjects with Stage III resectable melanoma will receive adjuvant therapy, nivolumab or ipilimumab plus nivolumab, based on whether a pathologic complete response (CR) or near CR (less than 10% viable tumor cells) is achieved with one dose of nivolumab in the neoadjuvant setting followed by surgery.
 Adjuvant Nivolumab in Resected Lung Cancers (ANVIL)  A Randomized Phase III Study of Nivolumab After Surgical Resection and Adjuvant Chemotherapy in Non-Small Cell Lung Cancers
99 years or below
All genders
Phase 3
The purpose of this study is to find if adding the study drug, nivolumab (also known as OPVIDO), will limit lung cancer from growing back in patients with early stage non-small cell lung cancer. Nivolumab is a drug that may turn on the body's immune system to attack any cancer …
 Evaluation of Corneal Confocal Microscopy in Ocular Surface Disease and/or Neuropathic Pain Patients
99 years or below
All genders
The purpose of this study is two-fold. Since there is currently no FDA approved software to analyze these images, the images taken will be used to help improve and refine current software, or help develop new software, in the hopes that it will be approved by the FDA. The images …
 Clinical Outcomes Assessment of the MitraClip Percutaneous Therapy for High Surgical Risk Patients
1 years - 99 years
All genders
Phase 4
This is a study of the MitraClip, percutaneous mitral valve repair system in patients with moderate to severe to severe functional mitral regurgitation who need surgical repair but are deemed not appropriate for surgery. Patients will be randomized in a 1:1 fashion to treatment with the Mitra Clip system or …
18 years - 99 years
All genders
The goal of this study is to determine whether those who have had Legionnaires' disease suffer smell loss.
 Preliminary Evaluation of Septin9 in Familial Adenomatous Polyposis Patients
1 years - 99 years
All genders
The purpose of this research study is to collect blood samples and applicable medical history from subjects diagnosed with hereditary colon cancer syndromes like FAP, Lynch Syndrome and MYK-associated polyposis and their family members. These samples will be used to evaluate the ability of a blood test to provide early …
 Hypoglossal Nerve Stimulation for Obstructive Sleep Apnea on Sympathetic and Vascular Function
21 years - 99 years
All genders
The hypoglossal nerve controls tongue movement. The Inspire® sleep implant works by stimulating this nerve. This process is called hypoglossal nerve stimulation, or “HGNS.” In this study, we are interested in seeing how HGNS affects blood pressure and heart-related measures and if it lowers the risk of heart problems in …
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