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Found 6 Vaccines trials

A listing of Vaccines medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19
18 years - 100 years
All genders
HVTN 405/HPTN 1901 will describe immune responses in study participants with a history of recovering from SARS- CoV-2 infection. A main aim of HVTN 405/HPTN 1901 is to develop antibody assays that can be reliably used to detect SARS-CoV-2 infection in vaccine and monoclonal antibody studies to prevent COVID-19. This …
 T-Cell Response to Vaccination
18 years - 65 years
All genders
The purpose of this study is to see how your body responds to a vaccine and how your body forms a protective response after vaccination. In this study we will use the yellow fever vaccine, an FDA approved vaccine that is commonly given to people traveling to certain parts of …
99 years or below
All genders
The purpose of this study is to obtain lymph node samples to understand how the immune system makes a response to vaccinations. In particular, we will study the immune cells within lymph nodes, where we think important parts of the vaccine response occur. We believe that if we study only …
99 years or below
All genders
Since its emergence, SARS-Cov2 has rapidly and widely spread across the globe due to lack of prior protective immunity in the human species. With widespread mitigation measures, all efforts focused on generating effective vaccination strategies that will provide herd immunity and protect the most vulnerable populations. However, there is very …
 A5369: HIV-1-Gag Conserved-Element DNA Vaccine (p24CE) as Therapeutic Vaccination in HIV-Infected Persons with Viral Suppression on Antiretroviral Therapy
99 years or below
All genders
Phase 1
A5369 is a phase I/IIa, randomized, double-blind, placebo-controlled study to evaluate the safety, immunogenicity, and efficacy of p24CE/full-length Gag DNA, as a therapeutic vaccine in HIV-1 infected persons. The study targets to enroll 40 participants. All participants are well-suppressed on ART, current CD4 T cell counts greater than 500 cells/mm3, …
 Profiling and Perturbing the Human Immune System to Understand the Human Immune Network
18 years - 99 years
All genders
This study aims to compare IBD patients with healthy controls to obtain a systems-level view of immune system perturbation by IBD. This intervention (anti-TNF therapy) will be intended to treat IBD but will also represent a major, broad immune system perturbation. Although the response of the patient in terms of …