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Found 18 Allergy trials

A listing of Allergy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Investigation of the Effect of Branched Chain Amino Acids on Fat-Induced Insulin Resistance in Healthy Adults.
18 years - 39 years
All genders
Phase 1
Elevations in plasma levels of branched chain amino acids (BCAAs, comprising leucine, valine, and isoleucine), a large component of protein, are strongly associated with insulin resistance and type 2 diabetes, but mechanisms for this relationship are unclear. This protocol will determine whether excess BCAAs worsen free fatty acid-induced insulin resistance. …
 UPCC 34810 The Cardiovascular Effects of Sunitinib Therapy:  Off-Target Changes in Cardiac Metabolism and Ventricular-Vascular Mechanics (CREST)
1 years - 99 years
All genders
Tyrosine kinase inhibitors such as sunitinib are used in the treatment of renal cell carcinoma and have significant off-target effects with cardiac toxicity and resultant ventricular cardiac dysfunction being a major concern. However, the mechanisms of these effects in humans remains poorly defined, as are the clinical methods to risk …
 Autism Spectrum Program of Excellence
3 years - 99 years
All genders
The goal of the ASPE study is to investigate the genetic basis of Autism spectrum disorder (ASD) and autism-related traits.Individuals 3 years old or older with a diagnosis (or suspected diagnosis) of autism spectrum disorder without intellectual disability may be eligible to participate. We are also recruiting individuals with a deletion or …
 Efficacy, Safety, and Tolerability Topical Nasal Spray in the Prevention of SARS-CoV-2 Infection in Healthcare Personnel
18 years - 90 years
All genders
Phase 2
Interventional
The purpose of this study is to assess the effectiveness, safety, and tolerability of GLS-1200 to prevent SARS-CoV-2 infection in healthcare personnel. GLS-1200 contains quinine diluted in saline (salt water). Pre-clinical studies have shown that quinine stimulates nasal cells to secrete compounds that may prevent growth of bacteria and reduce viruses …
 (PREDICT) A Multi-Center Study in Patients Undergoing Anthracycline-Based Chemotherapy to Assess the Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment
1 years - 99 years
All genders
Over the past 2 decades, there has been a significant increase in life span of patients with cancer so that now, there are more than 10 million cancer survivors in the U.S. [1]. There is a growing recognition that although survival has improved, many long-term side effects including cardiac complications …
 Determination of B-cell responsiveness to the incretin hormones GLP-1 and GIP in Cystic Fibrosis (PRIME)
18 years - 99 years
All genders
The mechanisms underlying cystic fibrosis related diabetes (CFRD) pathophysiology must be better defined if care for people with CFRD is to be optimized or if development of CFRD is to be interrupted. Detailed studies of insulin secretion in CF are required to achieve this goal since 1) subtle insulin secretion …
 Medtronic Evaluation of Multi-Electrode Phased RF Technology in Persistent Atrial Fibrillation
1 years - 99 years
All genders
Phase 3
The study is expected to be conducted at approximately 40 centers located in Europe, Canada and the United States to support US Food and Drug Administration (FDA) marketing application. A maximum of 350 subjects will be enrolled in the study to ensure 300 subjects can be evaluated for the primary …
 Using Natural Language Processing to Identify Depression in Patients with HIV
18 years - 99 years
Male
The purpose of this study is to develop algorithms that may help detect depressive symptoms in social media posts, specifically among men who have sex with men and who have HIV.
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