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Found 18 Depression trials

A listing of Depression medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 Genetics of Alcohol Dependence and Withdrawal in African Americans
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18 years - 100 years
All genders
The purpose of this study is to learn things that will help us better understand alcohol dependence, other kinds of substance dependence, and aspects of personality and behavior in African Americans. DNA, the material that carries genetic instructions, will be taken from blood, and used to study genes for these …
 A Randomized, Double-blind, Active-controlled Trial to Assess the Efficacy and Safety of AXS-05 Administered Orally to Subjects with Treatment Resistant Major Depressive Disorder
18 years - 65 years
All genders
We are currently enrolling participants for a clinical research study to look at the effectiveness and safety of an investigational medication AXS-05 (a combination of bupropion and dextromethorphan) compared to bupropion (Approved by FDA), in patients with depression who have not responded to prior treatment with at least one antidepressant. …
 Transcranial Magnetic Stimulation (TMS) Treatment for Post-Traumatic Stress
18 years - 60 years
All genders
Phase 1
Evaluates novel Transcranial Magnetic Stimulation (TMS) methods for the treatment of post-traumatic stress disorder (PTSD) and depressive symptoms to determine which strategies provide the greatest benefit to patients. Transcranial Magnetic Stimulation (TMS) is a non-invasive brain stimulation technique FDA-approved for the treatment of major depressive disorder (MDD) and obsessive compulsive …
 Computer-Assisted Therapy for Depression
18 years - 60 years
All genders
The purpose of this study is to learn more about the treatment success of Computer-augmented Cognitive Behavioral Therapy (CCBT) and examine the neural connections of patients with depression via functional Magnetic Resonance Imaging (fMRI) scans.Computer-augmented Cognitive Behavioral Therapy (CCBT) is approved by the FDA as a form of treatment for …
 DEPRESSION STUDY: INVESTIGATING LINKS BETWEEN SLEEP AND MOOD
25 years - 50 years
Female
GOAL: This research study aims to examine the role of slow-wave sleep activity in improving mood in individuals with Major Depressive Disorder (MDD).TARGET POPULATION: We are looking for 40 currently depressed males and females and 20 healthy controls with no history of depression between the ages of 25-50. Participants must …
 Depression Study-- Neuroimaging and Transcranial Magnetic Stimulation (TMS)
18 years - 60 years
All genders
We are recruiting individuals suffering from depression for a research study focused on the neuroscience behind depression and stress. Our study uses a mechanism called transcranial magnetic stimulation, or TMS, which is an FDA-approved treatment method for major depression. We are hoping to improve targeting methods for TMS, as well …
 Investigating the Role of Slow-wave Activity as a Marker of Impaired Plasticity in Major Depressive Disorder
25 years - 50 years
All genders
This research study aims to examine the role of sleep slow-wave activity (SWA) in modulating mood by testing the model that disrupting SWA during sleep can prevent homeostatic decreases in plasticity, thereby increasing plasticity and improving mood in individuals with MDD. Forty males and females with MDD (25-50 yo), and …
 Trial to Evaluate the Efficacy, Safety, and Tolerability of Brexpiprazole as Adjunctive Therapy in the Maintenance Treatment of Adults With Major Depressive Disorder
18 years - 100 years
All genders
Phase 3
You are being asked to take part in this study because you have been diagnosed with major depressive disorder (depression). Brexpiprazole is a medication being studied as a possible treatment for adjunctive treatment for Major Depressive Disorder (MDD). It was first approved in the United States (10 July 2015) for …
 An Open-Label Study to Assess the Long-term Safety and Efficacy of AXS-05 in Subjects with Major Depressive Disorder
99 years or below
All genders
Phase 3
This study is a multi-center, open-label trial to evaluate the long-term safety and efficacy of AXS-05 in subjects with major depressive disorder (MDD). Eligible subjects must have completed a prior MDD study with AXS-05 (AXS-05-301 or AXS-05-MDD-301) immediately prior to enrollment in this study.
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