Found 28 Congestive Heart Failure trials
A listing of Congestive Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
This study aims to understand the benefits/risks of Entresto in NYHA III-IV patients.
This study is assessing the safety and tolerability of an interatrial septal device implanted for those who have a dilated left atrium or some degree of diastolic dysfunction. This is often known as preserved ejection fraction heart failure. This study is blinded over the course of 2 years, and there …
The purpose of this study is to: assess if the iVAS can help improve blood circulation, gain a better understanding of how this device could impact your health, determine human interaction with the device, and assess the portability of this device.
This study is enrolling newly diagnosed heart failure (within 6 months from diagnosis) patients with no known cause for their heart disease. We are utilizing already used technology, voltage mapping capabilities used in electrophysiology procedures, to more directly target weaker areas of the left and right ventricles. our physicians would …
Please see section 1 of the full protocol
The study is being conducted to understand why the skeletal muscle of patients with Heart Failure with Preserved Ejection Fraction (HFpEF) does not work as well as the muscle of individuals without heart failure. This study seeks to understand whether the problem is with blood and oxygen delivery to the …
This is a multicenter, exploratory, open-label study to explore the efficacy and/or pharmacodynamic effect, PK, safety, and tolerability of mavacamten in approximately 35 ambulatory participants with symptomatic HFpEF and elevated cTnI and/or elevated NT-proBNP as defined in inclusion/exclusion criteria. The study will include an up to 7-week screening period (with …
This study will test whether Potassium Nitrate (KNO3), with and without Propionyl-L-Carnitine (PLC) and Nicotinamide Riboside (NR), improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity (SkM OxPhos) in participants with Heart Failure with Preserved Ejection Fraction (HFpEF). This study will also test whether the response to supplemental oxygen …
Veno-arterial (VA) extra-corporeal membrane oxygenation (ECMO) is indicated as a haemodynamic rescue strategy in decompensated acute or chronic heart failure presenting as cardiogenic shock. VA ECMO has a number of effects on the circulation including (i) perfusing end-organs, (ii) ventricular unloading, and (iii) improved coronary perfusion. It is a bridge …
