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Found 18 Alzheimer's Disease trials

A listing of Alzheimer's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 18-Month Study With an Open-Label Extension Phase to Confirm Safety and Efficacy of BAN2401 in Subjects With Early Alzheimers Disease
18 years - 99 years
All genders
Phase 3
BAN2401-G000-301 (Study 301) is an 18-month treatment (Core Study), multicenter, double-blind, placebo-controlled, parallel-group study in subjects with EAD (mild cognitive impairment [MCI] due to AD with intermediate likelihood/Prodromal AD or mild AD dementia) with confirmed amyloid pathology indicated by either positive amyloid load confirmed by amyloid PET assessment or CSF …
 Chronic insomnia and CSF markers of dementia
30 years - 50 years
All genders
The purpose of this study is to identify the relationship between chronic sleep disturbance and chemicals in spinal fluid that are related to dementia and a molecule called orexin that helps regulate wakefulness and appetite in the brain. Individuals with sleep problems and good sleepers will be asked to participate.
 Healthy Patterns Sleep Intervention for Persons with Memory and Sleep Problems and their Caregivers
60 years - 90 years
All genders
Phase 3
The Healthy Patterns Study intervention is a home-based activity intervention designed to introduce activities and education that promote healthy sleeping habits and improve well-being for those suffering with memory and sleep issues . Principal Investigator: Nancy A. Hodsgon, PhD, RN, FAAN, Nursing School, University of Pennsylvania
99 years or below
All genders
The longstanding view has been that insomnia, and other forms of sleep disturbance, emerge as a consequence of dementia and are the result of progressive neuronal damage. However, there is growing evidence that the direction of causation may go both ways, with sleep disturbance potentially increasing vulnerability to dementia. Longitudinal …
18 years - 85 years
All genders
Interventional
This study is designed to determine the changes in the brain that occur during conditions of verbal stimulation in patients who have Parkinson’s Disease and Parkinson’s Disease with Dementia or Dementia with Lewy Bodies.
 Four-Repeat Tauopathy Neuroimaging Initiative
99 years or below
All genders
New treatments that target the protein tau are beginning to enter human clinical trials. While tau-related therapies hold great promise for AD, clinical trials focusing on pure tauopathies are appealing because these diseases do not exhibit concurrent amyloid pathology. Pure 4 microtubule binding repeat (4R) tauopathies (4RT) include corticobasal degeneration …
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