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Found 699 none trials

A listing of none medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 PRELIMINARY STUDY OF OPTICAL BIOMARKERS FOR NEURODEGENERATION IN CHRONIC CEREBROVASCULAR DISEASE
99 years or below
All genders
This research study will test whether a new optical device can reliably measure markers of blood flow and blood vessel function in the brain. We will be recruiting 60 subjects in total: 30 healthy, 15 with known narrowing of the carotid artery, and 15 small vessel stroke. All subjects will …
 Evaluation of Corneal Confocal Microscopy in Ocular Surface Disease and/or Neuropathic Pain Patients
99 years or below
All genders
The purpose of this study is two-fold. Since there is currently no FDA approved software to analyze these images, the images taken will be used to help improve and refine current software, or help develop new software, in the hopes that it will be approved by the FDA. The images …
I
Investigator user1
99 years or below
Female
Phase 1
Please see section 3 of the full protocol Please see section 3 of the full protocol Please see section 3 of the full protocol
 Effect of Organic Nitrates and Hydralazine on Wave Reflections and Left Ventricular Structure and Function in Heart Failure with Preserved Ejection Fraction
1 years - 99 years
All genders
Phase 1
The purpose of this study is to test the effect of prolonged therapy (24 weeks) with isosorbide dinitrate ± hydralazine on arterial wave reflections, exercise capacity, left ventricular (LV) mass/fibrosis and diastolic function in patients with Heart Failure and Preserved Ejection Fraction (HFPEF). This is a double-blind, placebo-controlled pilot randomized …
 Substrate targeted ablation using the Cool Flex catheter ablation system for the reduction of Ventricular Tachycardia
1 years - 99 years
All genders
Phase 3
The purpose of the study is to compare the effectiveness of the Cool Flex Irrigated Catheter Ablation System to routine drug therapy without ablation to treat VT or prevent VT from developing in patients at risk. The study will also evaluate the safety of the catheter device. Information on the …
 Safety of Oral Anticoagulation Therapy Withdrawal after Successful Pulmonary Vein Antrum Isolation in Patients with Atrial Fibrillation and Associated High Risk Factors for Embolic Events (OAT Pilot Study)
1 years - 99 years
All genders
The purpose of the study is to assess the safety of stopping oral anticoagulation therapy (OAT) in patients who have undergone a successful ablation procedure for atrial fibrillation. A successful ablation procedure for atrial fibrillation is defined by the protocol as being arrhythmia free 3 months after the procedure. The …
 A Randomized  OPen-label Active controlled Multi-center Study to Evaluate the Safety of Rivaroxaban and Vitamin K Antagonists in Subjects Undergoing Catheter Ablation for Atrial Fibrillation
1 years - 99 years
All genders
In order to achieve 200 per-protocol subjects, approximately 250 eligible subjects, age 18 years or older, with a history of paroxysmal or persistent NVAF who are scheduled to undergo an elective catheter ablation procedure will randomize in a 1:1 ratio to receive either rivaroxaban 20 mg orally, once-daily, preferably administered …
21 years - 70 years
Accepts healthy volunteer
All genders
The Serenity Study is a voluntary research study that will investigate different approaches to stress management in order to help lower blood pressure. You may be eligible to participate if you: have blood pressure in the pre-hypertensive range (systolic BP 120-139 or diastolic BP 80-89), are a healthy adult between …
 FES PET/CT in Endocrine Refractory Breast Cancer
18 years - 99 years
Female
Phase 3
Patients with recurrent or metastatic ER+ breast cancer, who have failed prior endocrine therapy may be eligible for this study.  Patients may participate in this study, if they are at least 18 years of age, most participants will be receiving care at the clinical practices of the University of Pennsylvania. …
 Trauma Induced Coagulapathy and Inflammation
99 years or below
All genders
While a number of factors are known to be associated with the development of trauma induced coagulopathy (TIC), inflammation, and multi-organ failure, we currently cannot predict which patients are at risk for developing these life-threatening conditions with any certainty. In this prospective observational study, we will investigate the many factors …
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