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Found 697 none trials

A listing of none medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Sub-study of L-RAD (832203): Collection of Tissue and Fluid Samples for Research in Lymphoproliferative Disorders

99 years or below
All genders
To support the research of lymphoproliferative disorders (LPDs) by supplementing the main repository (IRB #832203) with biospecimens (i.e., tissue and fluid) obtained solely for the purpose of research. These materials will be used for future, unspecified research.
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A phase II open-label study of ONC201 in adults with recurrent high-grade glioma

99 years or below
All genders
Phase 2
This is A phase II, open-label study of ONC201 in adults with recurrent high- grade glioma. Subjects will be age 18 or older with a histone H3 K27M mutant glioma that has progressed after radiation therapy. The primary objective is to estimate the overall response rate (ORR) of ONC201 in …
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An open-label multi-center roll-over study to assess long

99 years or below
All genders
Phase 3
The purpose is to evaluate the long-term safety of osilodrostat in patients who have already received osilodrostat treatment in a previous Novartis trial for treatment of Cushing's syndrome.
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UPCC 45419: Phase I Study of Tasquinimod Alone and in Combination with Standard Therapy for Relapsed or Refractory Myeloma

99 years or below
All genders
Phase 1
The research study is being conducted to understand the effects of tasquinimod, an experimental medication, on patients with myeloma. Eligibile subject have multiple myeloma that has been previously treated and is now in need of additional treatment. Part 1 of this study evaluates tasquinimod alone. Part 2 of this study …
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Treatment for Mixed Urinary Incontinence: Mid-urethral Sling vs. Botox A

99 years or below
All genders
ABSTRACT Mixed urinary incontinence (MUI), defined as the presence of both stress urinary incontinence and urgency urinary incontinence, is a challenging condition for which clinicians frequently use multiple sequential treatments that have undergone limited head to head comparison in rigorous clinical trials. Mid-urethral Sling vs. Botox A (MUSA) is a …
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A Clinical Trial to Evaluate the Safety and Efficacy of Staged Bilateral Exablate Treatment of Medication Refractory Essential Tremor

99 years or below
All genders
The Exablate Model 4000 Type-1.0/1.1 Neuro system involves using an advanced, non-invasive technique currently approved by the Food and Drug Administration (FDA) to treat one side of your brain in a procedure called a thalamotomy (lesion the thalamus). This procedure involves performing an ablation (lesion) of an area of the …
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RADVAX FOR RELAPSED/REFRACTORY NON-HODGKIN LYMPHOMA: A PHASE II TRIAL OF PEMBROLIZUMAB + LOW DOSE RADIOTHERAPY

99 years or below
All genders
Phase 2
We plan to treat subjects with pembrolizumab in combination with radiation therapy to see if the combination is an effective treatment for relapsed/refractory non-Hodgkin lymphoma.
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Spironolactone for Regulating Blood Pressure after Intracerebral Hemorrhage

99 years or below
All genders
The purpose of this research study is to determine whether blood pressure treatment regimens with spironolactone are better than blood pressure treatment regimens without spironolactone at lowering blood pressure in hemorrhagic Stroke survivors. This study will randomize a total of 200 patients, 100 of each white and nonwhite patients, between …
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THE AURORA STUDY- Longitudinal Assessment of Post-traumatic Syndromes

99 years or below
All genders
See Protocol Section 1
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UPCC 23220 Vitamin D Receptor Agonist Paricalcitol Plus Gemcitabine and Nab-Paclitaxel in Patients with Metastatic Pancreatic Cancer

99 years or below
All genders
Phase 1
This research study consists of a safety run-in phase and a randomized phase 2 study which include subjects with previously-untreated, metastatic pancreatic adenocarcinoma. In the run-in safety study, the safety of adding two formulations (IV or Oral) of paricalcitol to a standard chemotherapy program of gemcitabine and nab-paclitaxel will be …
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