Found 696 none trials
A listing of none medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Elevations in plasma levels of branched chain amino acids (BCAAs, comprising leucine, valine, and isoleucine), a large component of protein, are strongly associated with insulin resistance and type 2 diabetes, but mechanisms for this relationship are unclear. This protocol will determine whether excess BCAAs worsen free fatty acid-induced insulin resistance. …
To evaluate the efficacy of tisagenlecleucel therapy among adult patients with refractory or relapsed follicular lymphoma as measured by complete response rate determined by Independent Review Committee in the full analysis set based on Lugano 2014 classification response criteria.
Medication is FDA approved. The present study is a further evaluation of the behavioral pharmacotherapeutic strategy (i.e., partial reinforcement following the obtention of treatment response with standard treatment) with a particular focus on 1) how low a dose may be used (dose = frequency of active medication) and 2) how …
A phase 2, randomized, placebo-controlled study designed to evaluate the efficacy and safety of repeated doses of evinacumab in adult patients with severe hypertriglyceridemia. The study consists of screening period (up to 37 days), a baseline/single-blind placebo run in period, a 12-week double-blind treatment period, a single-blind 12 week treatment …
The purpose of this study is to determine the safety and tolerability of pembrolizumab in people with lymphoma whose lymphoma relapsed or did not respond after receiving at least one prior treatment for lymphoma. This study will also determine how well patients with lymphoma respond to pembrolizumab.
Trimethoprim-sulfamethoxazole (TMP-SMX; Bactrim) is an FDA-approved drug for the treatment of infections and commonly used for 2 weeks or less. The purpose of this study is to observe the changes in the microbiome in your nose before, during, and after taking TMP-SMX for 4 weeks. The extended duration of TMP-SMX …
The purpose of this study is to evaluate the therapeutic benefit for participants receiving Recovery-Oriented Cognitive Therapy (CT-R) for families- a cognitive therapy based group for family members of individuals in the early stages of psychosis. A CT-R based intervention has shown to be effective for individuals with psychosis, offers …
This is a single-center, phase II, single-arm, open label study evaluating the efficacy and safety of abemaciclib for patients with recurrent oligodendroglioma (molecularly defined per the WHO 2016 guidance, i.e., presence of IDH mutation and 1p19q codeletion). The study will enroll 10 subjects who are evaluable for the studys primary …
Mortality related to cardiovascular disease in the US is improving. Yet the rate of decline is less for women than for men. Womens health is unique due to the varying reproductive stages, and differences are even greater due to gender-specific characteristics of the heart and vasculature. While women have some unique risk factors, …
