A listing of none medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
The purpose of the study is to compare how amlodipine versus metoprolol effect blood pressure in people with HFpEF. While hypertension is the most common risk factor for HFpEF, there is little evidence on the potential role of common antihypertensive medications, specifically calcium channel blockers (like amlodipine) and β-blockers …
We plan to enroll up to 25 (target of 20 fully evaluable) adult subjects in this study who have an established diagnosis of advanced cardiac amyloidosis (AL). Subjects will be included in 2 subject cohorts of approximately 10 subjects each. In one cohort positron emission tomography/computed tomography (PET/CT) imaging will …
Lymphoma survivors who were treated with prior radiation therapy have been shown to have an increased risk of cancers of the gastrointestinal system. This increased cancer risk may be due to damage to cells in your gastrointestinal system that is caused at the time of radiation. This research is being …
This research study aims to examine the role of sleep slow-wave activity (SWA) in modulating mood by testing the model that disrupting SWA during sleep can prevent homeostatic decreases in plasticity, thereby increasing plasticity and improving mood in individuals with MDD. Forty males and females with MDD (25-50 yo), and …
The purpose of this study is to learn how to dialysis doctors can treat dialysis patients infected with Hepatitis C themselves. Hepatitis C infection is common in hemodialysis patients. There are new medications, such as Zepatier, which can cure hepatitis C in > 95% of patients. Zepatier is particularly good …
The purpose of this clinical study is to evaluate safety of the study treatment, its effects on the immune system and on GBM. The study treatment includes three experimental parts: Two experimental products, INO-5401 + INO-9012, will be delivered into your muscle by an electroporation device called CELLECTRA® 2000.The third experimental …
The research study is being conducted to study the PD-1 antibody, AGEN2034 alone, or in combination with the CTLA-4 antibody, AGEN1884, in women with recurrent cervical cancer. Subjects will be asked to complete the following research procedures: 12 lead electrocardiogram (ECG) and evaluation of heart function (to determine heart health). …
The purpose of this study is to compare the effectiveness of gilteritinib to midostaurin in patients receiving standard combination chemotherapy for FLT3 AML. Eligible untreated patients with FLT3 acute myeloid leukemia (AML) between the ages of 18 and 65 will be randomized to receive gilteritinib or midostaurin during induction and …
The research study is being conducted to test a new investigational imaging agent called 89Zr-Df-IAB22M2C with positron emission tomography/computed tomography (PET/CT) scans on subjects with cancer who plan to be treated as part of the clinical care. The imaging agent could help the doctor see where your CD8+ T cells …
SGM-101 is a fluorochrome-labeled anti-carcino-embryonic antigen (CEA) monoclonal antibody. What this means is that part of SGM-101 is a chemical that is attracted to and will attach to the cells of your cancer. Another part of SGM-101 is a chemical that will glow when infrared light is shined on it. …