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Found 698 none trials

A listing of none medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 AMC 083 / UPCC 12716: Tissue Acquisition for Analysis of Prognostic Factors  Immunology  and Genetic Progression of HIV-1 Associated Malignancies
18 years - 99 years
All genders
The main purpose of this study is to collect tissue from people diagnosed with HIV-associated cancer. We will use these samples to look for genetic changes associated with HIV- and other virus-related cancers. This may lead to better ways of preventing, detecting, and treating HIV-associated cancers.
18 years - 99 years
All genders
Phase 3
The purpose of this study is to compare any good and bad effects of using 2 years of the investigational drug Palbociclib in combination with standard anti-hormone therapy to using standard anti-hormone therapy alone and to evaluate the likelihood that invasive breast cancer returns.
 Detection of cell-free circulating tumor DNA in patients with glioblastma undergoing treatment with first-line chemoradiotherapy
99 years or below
All genders
Glioblastoma (GBM) is the most common primary brain tumor in adults and is uniformly fatal. During standard adjuvant treatment for GBM following initial surgical resection of the tumor, patients are treated with a combination of radiation and chemotherapy. During and after this adjuvant treatment, patients are monitored for disease progression …
 Targeting the Cholinergic Pathway in HIV-associated Inflammation and Cognitive Dysfunction
40 years - 100 years
All genders
Although anti-retroviral therapy (ART) enhances life expectancy and overall quality of life (QoL), HIV-infected individuals are increasingly vulnerable to non-AIDS-related diseases including HIV-associated neurocognitive disorders (HAND). Inflammation is a primary mechanism in the pathogenesis of HAND and tobacco use may further exacerbate inflammation. Conversely, nicotine alone has anti-inflammatory effects suggesting …
 A Randomized  Multicenter Study for Isolated Skin Vasculitis (ARAMIS)
99 years or below
All genders
The purpose of this study is to evaluate different treatment options for patients with skin vasculitis (also named cutaneous vasculitis). Patients with isolated cutaneous small vessel vasculitis, medium-sized vessel vasculitis (polyarteritis nodosa), or IgA vasculitis (Henoch-Schönlein purpura) can join this study. The frequently used treatments for skin vasculitis are colchicine, …
 A Randomized  Double-blind  Placebo-controlled Clinical Study to Evaluate Mavacamten (MYK-461) in Adults with Symptomatic Obstructive Hypertrophic Cardiomyopathy
99 years or below
All genders
Phase 3
This is a Phase 3, double-blind, randomized, placebo-controlled, multicenter, international, parallel-group study to evaluate the safety, tolerability, and efficacy of mavacamten compared with placebo (1:1) in participants with symptomatic oHCM. Approximately 220 participants will be enrolled. This includes ~80 participants (~40 per treatment group) who consent to participate in a …
 Prevention of Mortality with Long-Term Administration of Human Albumin in Subjects with Decompensated Cirrhosis and Ascites
99 years or below
All genders
Phase 3
This study is designed to evaluate the effects of Albutein 20% infusion on long-term survival (1-year transplant-free) in liver cirrhosis compared to the Standard Medical Treatment (SMT).
 Randomized Evaluation of Redo Ablation Procedures of Atrial Fibrillation with Focal Impulse and Rotor Modulation Guided Procedures
99 years or below
All genders
An algorithm that has been licensed for use with a novel mapping technology (RhythmView, Abbott Electrophysiology (Topera, Inc.), Menlo Park, CA) for analyzing atrial recordings during human AF, finding that greater than 95% of cases demonstrate either a rapidly spinning rotor (small circuit) or very rapid focal impulse formation. Catheter …
 EVALUATION OF PATIENT OUTCOMES FROM THE KIDNEY ALLOGRAFT OUTCOMES ALLOSURE REGISTRY (KOAR)
99 years or below
All genders
This is a multicenter, non-blinded, prospective observational cohort study of 1000 patients enrolled in an AlloSure testing registry, including 300 patients at centers with planned renal surveillance biopsies at 12 months post-transplantation. The other 700 patients will be from centers that do not perform protocol surveillance biopsies. This registry study …
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