Found 15 genetics trials
A listing of genetics medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
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The purpose of this study is to learn things that will help us better understand alcohol dependence, other kinds of substance dependence, and aspects of personality and behavior in African Americans. DNA, the material that carries genetic instructions, will be taken from blood, and used to study genes for these …
Eslicarbazepine acetate (Aptiom®) is an antiepileptic drug (AED) approved in the United States (US) as adjunctive therapy for the treatment of partial-onset seizures in adults .Prior research has shown that seizure medicines like carbamazepine (Tegretol®) and oxcarbazepine (Trileptal®, Oxtellar®) are more likely to cause severe drug related skin reactions in …
14.00 Normal 0 false false false EN-US X-NONE X-NONE We are looking for healthy volunteers to participate in a study to see if a particular type of medication (statin) has an impact on the kind of bacteria that are found in the gut, and if the gut bacteria affects how …
This study aims to understand the effects of potential familial/genetic links in an otherwise unclear origin of a patient's heart disease.
This is a longitudinal study of individuals with CMT looking at the natural history of the disease to see how it changes over time. Participants are invited back on a yearly basis to determine how the changes are occurring.
The well-established, consistent and precise phenotyping developed in the previous ARVC Registry (and published as the Modified Task Force Criteria), with a comprehensive primary genotyping approach, search for genetic modifiers, and biomarker analysis will fulfill the long-term goals of this proposal to identify the genetic basis of all forms of …
Subjects with unusual lipids in subjects with known or suspected genetic variants that may be associated with change in lipoprotein kinetics will have two-night, one-day inpatient stay in CHPS, during which they will undergo extensive evaluation of lipoprotein kinetics using stable isotope techniques, OFTT, and OGTT. Subjects will complete a …
The last 2 decades have witnessed a dramatic expansion in our understanding of the genetics, pathophysiology, and comorbidities of psoriasis leading to the development and approval of a variety of treatment strategies targeting pathways such as JAK/STAT, PDE4, TNF, IL12/23, and IL-17. We propose creating a biobank of specimens from …
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults and is near uniformly fatal. Only three treatments have been approved by the US FDA for GBM in the past 2 decades: temozolomide, bevacizumab, and, most recently, tumor-treating fields (TTFields). TTFields represents a novel anti-cancer modality that creates …
Multi-center, open-label, first in human (FIH) Phase 1 study of the safety, tolerability, feasibility, and preliminary efficacy of the administration of genetically modified autologous T cells (CART-TnMUC1 cells) engineered to express a chimeric antigen receptor (CAR) capable of recognizing the tumor antigen, TnMUC1 and activating the T cell (CARTTnMUC1 cells). …
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