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Found 13 metabolism trials

A listing of metabolism medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

18 years - 85 years
All genders
The purpose of this research study is to explore the effect of obstructive sleep apnea (OSA) on brain oxygen metabolism. This will show us how much oxygen your brain uses to function. OSA is known to lower levels of oxygen in the blood and also to cause cognitive deficits. We …
99 years or below
All genders
Glucose is a major energy source for brain cells. Changes in blood glucose also leads to changes in supply or availability of glucose to brain cells. Changes in various brain metabolites when mapped in different areas of the brain will allow, an understanding of the effects of such changes in …
 The influence of nicotinic hepatic metabolism on neuroreceptor substrates of nicotine addiction
18 years - 99 years
All genders
Phase 1
We will examine differences in nAChR availability based on individual differences in the nicotine metabolism rate. Work conducted by Dr. Lermans group at Penn, in collaboration with Drs. Rachel Tyndale (University of Toronto) and Neal Benowitz (University of California, San Francisco) has documented differences in smoking cessation and treatment response …
99 years or below
All genders
Phase 2
This study will test whether Potassium Nitrate (KNO3), with and without Propionyl-L-Carnitine (PLC) and Nicotinamide Riboside (NR), improves submaximal exercise endurance and skeletal muscle oxidative phosphorylation capacity (SkM OxPhos) in participants with Heart Failure with Preserved Ejection Fraction (HFpEF). This study will also test whether the response to supplemental oxygen …
 Does vaginal delivery of combined hormonal contraception affect the risk of metabolic syndrome in overweight/obese women with PCOS?
99 years or below
Female
Please see attached protocol under Section 1, titled "Background and Study Rationale".
 Effects of Insomnia Treatment on Metabolism in Patients with Depression
21 years - 60 years
All genders
800x600 Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Are you currently depressed and have trouble sleeping? Are you between the ages of 21 and 60? You may be eligible for one of our current research studies:Cognitive behavioral therapy for insomnia (CBT-I) has been the ‘gold standard’ for the …
 UPCC 34810 The Cardiovascular Effects of Sunitinib Therapy:  Off-Target Changes in Cardiac Metabolism and Ventricular-Vascular Mechanics (CREST)
1 years - 99 years
All genders
Tyrosine kinase inhibitors such as sunitinib are used in the treatment of renal cell carcinoma and have significant off-target effects with cardiac toxicity and resultant ventricular cardiac dysfunction being a major concern. However, the mechanisms of these effects in humans remains poorly defined, as are the clinical methods to risk …
 A randomized  double-blind  placebo controlled  multi-center study to assess the effect of ranolazine on outcomes in subjects with pulmonary hypertension and right ventricular dysfunction accompanied by a comparative study of cellular metabolism in subjects with pulmonary hypertension with and without right ventricular dysfunction
1 years - 99 years
All genders
A multi-center study evaluating the effects of ranolazine in subjects with class II/III/IV pulmonary hypertension on stable background therapy and persistent RV dysfunction. Study involves an observational arm and a 26-week treatment arm. At baseline (wk 0), interim (wk 13) and the conclusion of treatment period (wk 26) subjects will …
 Testtrial6944
18 years - 70 years
Female
Phase 2
19-80Testing as per condition
 Testtrial8107
18 years - 70 years
Female
Phase 2
19-80
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