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Found 53 administration trials

A listing of administration medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 XXXXXX- Xenon & Neural Inertia
99 years or below
All genders
This pilot study involves the administration of xenon gas via the ENHANCER 3000 delivery system to 12 healthy adult volunteers; xenon concentrations will range from 0% to up to 75%. Subjects will wear an Actiwatch for 7 days and nights prior to xenon administration (Study Day) and 7 days/nights afterwards. …
 UPCC 04717: Phase I  open label  dose-escalation study to evaluate the safety  expansion  persistence of a single dose of UCART19 (allogeneic engineered T-cells expressing anti-CD19 chimeric antigen receptor)  administered intravenously in patients with relapsed or refractory CD19 positive B-cell acute lymphoblastic leukaemia (B-ALL)
99 years or below
All genders
Phase 1
The main aims of this study are to test the safety of up to 4 different doses of UCART19, and to identify the best dose of UCART19, by measuring what has happened to the leukemia cells at day 28 (28 days after the administration of UCART19), day 84 (84 days …
 An open-label study to define the safety  tolerability and clinical activity of deutetrabenazine (Austedo) in adult study subjects with dystonia
18 years - 99 years
All genders
Phase 3
The purpose of this research study is to explore the safety and tolerability of the daily oral administration of deutetrabenazine, whose trade name is Austedo, in adults with dystonia.
99 years or below
All genders
Phase 3
This double-blind, randomized controlled trial will examine the safety and tolerability of the combination of intravenous administration of VB-111 and paclitaxel compared to placebo and paclitaxel in patients with platinum resistant ovarian cancer.
 Phase 1 Study of Autologous Anti-CD22 Chimeric Antigen Receptor Redirected T Cells (CART22-65s) alone and when co-administered with humanized Anti-CD19 Chimeric Antigen Receptor Redirected T cells (huCART19) In Patients with Relapsed or Refractory Acute Lymphoblastic Leukemia
99 years or below
All genders
Phase 1
This is a single center, single arm, open-label Phase 1 study with two cohorts to determine the safety and feasibility of infusing CART22-65s with or without huCART19 after administration of lymphodepleting chemotherapy in adult patients with relapsed or refractory B-ALL.
 An Open-Label  Safety and Tolerability Study of Chronic Intermittent Use of Diazepam Buccal Soluble Film (DBSF) in Adult Subjects With Epilepsy.
18 years - 99 years
All genders
Phase 3
Interventional
You are being asked to be in this study because you have epilepsy and you take epilepsy medication. Aquestive Therapeutics (the study Sponsor) has begun a research study of an investigational drug called Diazepam Buccal Soluble Film or DBSF as a possible treatment for patients with epilepsy. An investigational drug …
 Attain StarFix Model 4195 LV Lead Extraction Study
1 years - 99 years
All genders
The purpose of this study is to characterize the removability of the Attain StarFix®Model 4195 Left Ventricular (LV) Lead (StarFix®). The goal of the trial is to evaluate the lead removal success in patients that are indicated for left ventricular lead removal. This study is required by the Food and …
99 years or below
All genders
Phase 3
This trial is a phase 3, double-blind, placebo-controlled, randomized withdrawal maintenance trial of brexpiprazole in subjects who require adjunctive treatment of MDD designed to fulfill a post-marketing commitment to the US Food and Drug Administration (FDA). There is a paucity of data on long-term use of the combination of ADT …
 A Randomized, Multicenter Study of First-Line Ambrisentan and Tadalafil Combination Therapy in Subjects with Pulmonary Arterial Hypertension, “Ambition” Trial
18 years - 75 years
All genders
Phase 3
Interventional
This clinical research study involves an experimental combination of two drugs, ambrisentan and tadalafil for the treatment of Pulmonary Arterial Hypertension (a narrowing of the arteries connecting the lungs to the heart that leads to an increase in blood pressure). This is also known as PAH. These drugs have been …
 A Phase 2 Multicenter, Open Label, Randomized Study of Two Titration Regimens of Oral CXA-10 in Subjects with Primary Focal Segmental Glomerulosclerosis (FSGS)
18 years - 100 years
All genders
Phase 2
Interventional
Primary FSGS is a progressive disease that causes the kidneys to scar, to leak protein into the urine and may lead to kidney failure. This study is being done to see whether a new medication, called CXA-10, can reduce the amount of protein in the urine and maintain stable kidney …