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Found 8 neurosurgery trials

A listing of neurosurgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 CAROTID REVASCULARIZATION AND MEDICAL MANAGEMENT FOR ASYMPTOMATIC CAROTID STENOSIS TRIAL (CREST-2) PROTOCOL
35 years - 100 years
Non-Binary
CREST-2 is a national multicenter stroke prevention study that is actively enrolling participants with narrowing in their carotid artery WITHOUT stroke or stroke warning signs (TIAs or mini-strokes). This study is comparing intensive medical management alone to intensive medical management used in combination with a procedure to remove plaque buildup …
 PD GPI MRFGUS
30 years - 100 years
All genders
To demonstrate ExAblate procedure is safe and works.There is evidence in medical literature showing that by ablating a particular cluster of cells in the brain, dyskinesia (abnormal movements)&motor symptoms of PD may improve. ExAblate can be used to perform ablation more precisely in minimally invasive fashion. In this study we …
18 years - 100 years
All genders
Phase 4
You are being invited to participate in a research study because you have been diagnosed with Parkinson’s disease (PD) and you underwent or have been offered a procedure called Deep Brain Stimulation (DBS) as a treatment option to manage some of your symptoms of Parkinson’s disease. The purpose of this …
 A PHASE II STUDY EVALUATING THE EFFICACY AND SAFETY OF NIRAPARIB AND TUMOR-TREATING FIELDS IN RECURRENT GLIOBLASTOMA
22 years - 99 years
All genders
Phase 2
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults and is near uniformly fatal. Only three treatments have been approved by the US FDA for GBM in the past 2 decades: temozolomide, bevacizumab, and, most recently, tumor-treating fields (TTFields). TTFields represents a novel anti-cancer modality that creates …
 Randomized Study of Cranial Blocks for Postoperative Anesthesia to Reduce Pain and Postoperative Opioid Usage
18 years - 99 years
All genders
The research study is being conducted to look at the effectiveness of analgesia (pain medication) by scalp nerve block with various medications that will help doctors to more effectively control pain after surgery and for a longer period of time. 
18 years - 75 years
All genders
Phase 2
This is a multicenter, randomized, open-label study of Toca 511 and Toca FC versus standard of care (SOC) that comprises Investigators choice of either single agent chemotherapy (lomustine or temozolomide) or bevacizumab administered to subjects undergoing resection for first or second recurrence (including this recurrence) of glioblastoma or anaplastic astrocytoma. …
 A Randomized Multicenter Phase 2 Study of DSP-7888 Dosing Emulsion in Combination with Bevacizumab versus Bevacizumab Alone in Patients with Recurrent or Progressive Glioblastoma following Initial Therapy
18 years - 99 years
All genders
Phase 2
The BBI-DSP-7888-201G trial is designed to compare the overall survival (OS) between treatment with DSP-7888 Dosing Emulsion plus bevacizumab (Bev) versus Bev alone in patients with recurrent or progressive glioblastoma multiforme (GBM) following initial therapy. This is a randomized, active-controlled, multicenter, open-label, parallel groups, Phase 2 study. Approximately 200 patients …
 Detection of cell-free circulating tumor DNA in patients with glioblastma undergoing treatment with first-line chemoradiotherapy
99 years or below
All genders
Glioblastoma (GBM) is the most common primary brain tumor in adults and is uniformly fatal. During standard adjuvant treatment for GBM following initial surgical resection of the tumor, patients are treated with a combination of radiation and chemotherapy. During and after this adjuvant treatment, patients are monitored for disease progression …