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Found 10 rheumatology trials

A listing of rheumatology medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

 A Randomized, Double-Blind, Placebo-Controlled Multiple Ascending Dose Study of Intravenous ATYR1923 in Patients with Pulmonary Sarcoidosis
18 years - 93 years
All genders
Phase 1
This study is being done to learn more about the safety of an investigational drug called ATYR1923, and to find out more about the effects of different doses of this drug on the lungs of people who have pulmonary sarcoidosis. "Investigational" means that it is not approved by the United …
 Phase 1 Open-Label Study to Determine the Safety and Tolerability of AVID200, a Transforming Growth Factor B Inhibitor, in Diffuse Cutaneous Systemic Sclerosis
18 years - 90 years
All genders
Phase 1
This study is being done to learn more about the safety of the study drug, AVID200, and to find out more about the effects of different study drug doses in people with scleroderma.  AVID200 is referred to as an investigational drug because it is in the early stages of development …
 Study to Evaluate the Safety and Efficacy of Upadacitinib in Giant Cell Arteritis: SELECT-GCA
50 years - 100 years
All genders
Phase 3
The main purpose of this study is to understand how well giant cell arteritis (also known as temporal arteritis; GCA) responds to an investigational drug called upadacitinib. Upadacitinib is being tested to find out if it is safe and effective in treating GCA. An investigational drug is one that is …
 T-Cell Response to Vaccination
18 years - 65 years
All genders
The purpose of this study is to see how your body responds to a vaccine and how your body forms a protective response after vaccination. In this study we will use the yellow fever vaccine, an FDA approved vaccine that is commonly given to people traveling to certain parts of …
18 years - 99 years
All genders
The last 2 decades have witnessed a dramatic expansion in our understanding of the genetics, pathophysiology, and comorbidities of psoriasis leading to the development and approval of a variety of treatment strategies targeting pathways such as JAK/STAT, PDE4, TNF, IL12/23, and IL-17. We propose creating a biobank of specimens from …
18 years - 89 years
All genders
This study will help researchers better understand the management of psoriatic arthritis (PsA). The goals of this study are a) to better understand how PsA responds to biologic therapy b) to build a registry of data and blood from patients with PsA for future studies and c) to figure out …
18 years - 90 years
All genders
Phase 2
The purpose of this study is to see whether a drug called naltrexone improves health-related quality of life in patients with vasculitis. Naltrexone is a prescription drug approved for a different reason at a higher dose than the dose used in this study. However, “low dose naltrexone” is widely used, …
18 years - 99 years
All genders
Trimethoprim-sulfamethoxazole (TMP-SMX; Bactrim) is an FDA-approved drug for the treatment of infections and commonly used for 2 weeks or less. The purpose of this study is to observe the changes in the microbiome in your nose before, during, and after taking TMP-SMX for 4 weeks. The extended duration of TMP-SMX …
 Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Sarilumab in Giant Cell Arteritis
18 years - 87 years
All genders
Phase 3
The main purpose of this study is to understand how well giant cell arteritis (also known as temporal arteritis; GCA) responds to an investigational drug called sarilumab. Sarilumab needs to be tested to find out if it is safe and effective in treating GCA. An investigational drug is one that …
 Test Trial: Penn Insomnia Study
19 years - 83 years
Accepts healthy volunteer
All genders
this is a test study. test test test