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Found 55 medicine trials

A listing of medicine medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Program with 2 clinical trials
18 years or above
All genders
Phase 1
Interventional
APT-008 is an open-label, Phase I/Ib, dose escalation and expansion cohort study to evaluate the safety, tolerability, Pharmacokinetic (PK), Pharmacodynamic (PD), and preliminary efficacy of EOS301984 as monotherapy and in combination with other anticancer therapies in participants with advanced solid tumors.
 Genetics of Alcohol Dependence and Withdrawal in African Americans
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None
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None
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None
18 years - 100 years
All genders
The purpose of this study is to learn things that will help us better understand alcohol dependence, other kinds of substance dependence, and aspects of personality and behavior in African Americans. DNA, the material that carries genetic instructions, will be taken from blood, and used to study genes for these …
100 years or below
All genders
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 CAROTID REVASCULARIZATION AND MEDICAL MANAGEMENT FOR ASYMPTOMATIC CAROTID STENOSIS TRIAL (CREST-2) PROTOCOL
35 years - 100 years
Non-Binary
CREST-2 is a national multicenter stroke prevention study that is actively enrolling participants with narrowing in their carotid artery WITHOUT stroke or stroke warning signs (TIAs or mini-strokes). This study is comparing intensive medical management alone to intensive medical management used in combination with a procedure to remove plaque buildup …
 DCPMS: Dialated Cardiomyopathy Precision Medicine Study
1 years - 100 years
All genders
This study aims to understand the effects of potential familial/genetic links in an otherwise unclear origin of a patient's heart disease.
 EFFICACY AND SAFETY OF A ONCE-WEEKLY INJECTABLE MEDICINE IN PARTICIPANTS WITH OVERWEIGHT OR OBESITY. (REDEFINE 1)
J
James David
18 years - 100 years
All genders
Phase 1
This study has 2 parts: The first part is the main study and the second part is the extension study. During the main study participants will receive 1 of 4 study medicines. If participants continue in the extension study, they will not receive any study medicine during the extension. The …
 A study to evaluate an oral medication, Siponimod (BAF312), in patients with Secondary Progressive Multiple Sclerosis
18 years - 60 years
All genders
Phase 3
The main purpose of the study is to see how effective and safe BAF312 is compared to a Placebo in patients with Secondary Progressive MS. A placebo is a “pill” (capsule or tablet) with no medicine inside. A placebo is used to make sure that the changes you report are …
 TactiCath Post Market Approval Study
18 years - 100 years
All genders
Phase 4
The purpose of the research study is to obtain additional information safety and effectiveness of an FDA approved catheter when used to treat patients with Paroxysmal atrial fibrillation.
 World-wide Randomization Antibiotic Envelope Infection Prevention Trial (WRAP-IT)
1 years - 100 years
All genders
This study is a single-blinded,randomized,prospective, multi-center clinical trial. The study will evaluate the ability of the TYRX absorable Antibacterial Envelope to reduce major cardiovascular implantable electronic device (CIED) infections. Patients undergoing CIED generator replacement, upgrade, revision or new biventricular defibrillator system will be randomized to receive the TYRX envelope or …
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