Transcranial magnetic stimulation (TMS) is a non-invasive mechanism for stimulating brain regions in humans. TMS can potentiate or inhibit activity in various brain regions, and it allows researchers to exert causal control to explore and define network connectivity among brain regions. Using real-time brain readouts combined with interleaved TMS/fMRI, we will compare across subjects the optimal and the least optimal stimulation frequency based on individualized functional connectivity networks. By comparing brain and behavioral changes after three days of neuromodulation at either optimal or least optimal stimulation frequency, we aim to explore whether optimal stimulation frequency will lead to more robust brain and behavior responses to repetitive TMS (rTMS).

You may be eligible for this study if you meet the following criteria:

• Conditions: TMS, stimulation
• Age: 18 years - 99 years
• Gender: All