Clinical Research
Opportunities

Penn Medicine is conducting studies to develop new ways to prevent, diagnose, and treat disease. You might be eligible to participate

Penn Medicine is conducting studies to develop new ways to prevent, diagnose, and treat disease. You might be eligible to participate

Penn Medicine is conducting medical studies to develop new diagnostic and clinical treatments to improve current standards of care.

Recently Added/Updated trials

 A First-in-Human Study of EOS301984 as Monotherapy or Combination Therapy in Adult Participants With Advanced Solid Tumors

A First-in-Human Study of EOS301984 as Monotherapy or Combination Therapy in Adult Participants With Advanced Solid Tumors

18 years or above
All genders
Phase 1
Interventional
APT-008 is an open-label, Phase I/Ib, dose escalation and expansion cohort study to evaluate the safety, tolerability, Pharmacokinetic (PK), Pharmacodynamic (PD), and preliminary efficacy of EOS301984 as monotherapy and in combination with other anticancer therapies in participants with advanced solid tumors.
 Artificial Intelligence (AI) Assisted Real-time Adenoma Detection During Colonoscopies

Artificial Intelligence (AI) Assisted Real-time Adenoma Detection During Colonoscopies

45 years - 89 years
All genders
Interventional
This is a pragmatic, double-blind, randomized, controlled trial, to evaluate the effect of implementing a CADs system within the routine clinical practice of Canadian healthcare institutions.The main hypothesis of this study is that the ADR in the operating room equipped with the GI genius CADe system will be significantly higher than the ADR in the ordinary operating room.
 Cochlear Implant Speech in Noise Processing

Cochlear Implant Speech in Noise Processing

18 years - 99 years
All genders
Interventional
The study will help us in understanding the neural mechanisms by which listeners with a cochlear implant detect speech in noisy environments.
 Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19

Characterizing SARS-CoV-2-specific Immunity in Individuals Who Have Recovered From COVID-19

18 years - 100 years
All genders
HVTN 405/HPTN 1901 will describe immune responses in study participants with a history of recovering from SARS- CoV-2 infection. A main aim of HVTN 405/HPTN 1901 is to develop antibody assays that can be reliably used to detect SARS-CoV-2 infection in vaccine and monoclonal antibody studies to prevent COVID-19. This information will be critical in illuminating the path to the development and testing of safe and effective vaccine and antibody interventions to prevent COVID-19.
 Universal COVID-19 Biobank: A subset of the Penn Medicine BioBank

Universal COVID-19 Biobank: A subset of the Penn Medicine BioBank

18 years - 100 years
All genders
Observational
The Universal COVID-19 Biobank – a component of the Penn Medicine Biobank – is collecting and storing biological specimens as well as information about people who may or may not have been exposed to the SARS-CoV-2 virus as well as those who have developed COVID-19 disease. This information will be used to help learn more about the risk of developing COVID-19 after exposure, to better understand why different people have different reactions to the virus, why some people get very sick from the virus while others don’t, and to better understand the how other diseases and conditions influence the severity of COVID-19.

test cancer API Toggle ON

All genders
See protocol section 2 See protocol section 2 See protocol section 2. this is p tag. header

test cancer API Toggle OFF

All genders
See protocol section 2 See protocol section 2 See protocol section 2. this is p tag. header

Volunteer sign up

Participate in medical studies to develop new diagnostic and clinical treatments and improve current standards of care.

Healthy Volunteers

Currently seeking healthy volunteers for research studies.

Logo

CureTalks@Penn interviews Penn Medicine physicians about their cutting edge research and clinical trials. Our goal is to inform patients, care-givers, patient advocates and other physicians about research that occurs at Penn Medicine.

View More